Barseliv


Prescription

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Barseliv – physiologically nitrogen compounds are metabolized through the urea cycle to be eliminated in the form of ammonium by the kidney.

Composition

Each 10 ml contains: l-Ornithine-L-Aspartate – 5 g, water for injection BP q.s.

Indications for use

In hyperammonemia as a result of acute and chronicliver diseases such as:

  • liver cirrhosis
  • fatty liver
  • hepatitis
  • especially for the treatment of incipient disturbances of consciousness (pre-coma) or neurological complications (hepatic encephalopathy).

Since ornithine aspartate exerts its action in the metabolic cycles of the liver, elevated blood ammonia levels are rapidly lowered. The capacity of detoxification, particularly of the urea cycle, is enhanced.

Mode of application

For reasons of venous tolerance, should not more than 4 vials dissolved in 500 ml of solution.
In case of acute liver inflammation (acute hepatitis), recommended 8 vials a day.

In the pre-coma and hepatic coma may apply depending on the degree of severity up to 20 vials diluted in largevolume during the first day, according to the following dosage schedule that has proven effective:
8 vials for 6 hours, then 4 vials pass for 6 hours last administration can repeat this twice more to complete the 20 vials in one day. Duration of infusion, frequency, and duration of treatment is determined individually.
Maximum infusion rate – 5 g / h It is recommended to dissolve a maximum of 60 ml (6 vials) of the drug in 500 ml of infusion solution.